CHEM1011: Basic Chemistry-I

Credits: 3+1, Marks: 75 (Th: 40, Prac: 20, IA: 15)

Course Objective:

• Several fundamental aspects of inorganic, organic, and physical chemistry are discussed for the basic understanding of the students.
• The topics covered will help the students for studying higher in chemical sciences.
• Easy organic chemistry practical using several chemical and physical methods will enhance the basic knowledge of students’ hands-on training.

Course Outcome:

Students will be introduced with several basic aspects of theory and practical of chemical sciences. This will grow the foundation of the subject for studying various advanced topics in future semesters.

Theory (Credit: 3)

1. Atomic Structure (6 Hours): Bohr’s theory, its limitations, and atomic spectra of hydrogen atom; Sommerfeld’s theory; wave mechanics – de Broglie equation, Heisenberg’s uncertainty principle, Schrödinger’s wave equation, significance of ψ and ψ², quantum numbers, radial and angular wave functions for hydrogen atom, shapes of s, p, d, and f orbitals, Pauli’s exclusion principle, Hund’s rules, Aufbau principle, ground state term symbols for atomic number up to 30.
2. Periodic Properties (6 Hours): Modern IUPAC periodic table, effective nuclear charge, Slater’s rules, atomic radii, ionic radii, covalent radii, lanthanide contraction, ionization potential, electron affinity, electronegativity (Pauling’s, Mulliken’s, Allred-Rochow’s scales), group trends, periodic trends, secondary periodicity, relativistic effect, inert pair effect.
3. Acids and Bases (6 Hours): Arrhenius concept, solvent system theory (H₂O, NH₃, SO₂, HF), Bronsted-Lowry concept, Pauling’s rules, Lux-Flood concept, Lewis concept, solvent levelling, Drago-Wayland equation, superacids, HSAB principle, acid-base equilibria, pH, buffer, indicators, organic acids and bases, effect of structure, substituent, and solvent.
4. Fundamentals in Organic Chemistry (12 Hours): Electron displacement phenomena (inductive, field, hyperconjugation, mesomeric, resonance, electromeric, steric effects), bond properties, bond dissociation energy, bond distances, angles, Baeyer’s strain theory, melting/boiling points, solubility, polarity, dipole moments, reactive intermediates (carbocations, carbanions, radicals, carbenes, benzynes, nitrenes), aromaticity (Hückel’s rules, antiaromaticity, homoaromaticity), Frost diagram, delocalization energies.
5. Properties of Gases (4 Hours): Ideal and real gases, compressibility factor, Boyle temperature, van der Waals equation, Dieterici equation, critical state, virial equation, intermolecular forces (Debye, Keesom, London, Lennard-Jones potential).
6. Chemical Kinetics-I (5 Hours): Rate law, order, molecularity, rate constants, first-, second-, n-th order reactions, pseudo first-order reactions, determination of order, opposing, consecutive, parallel reactions, Arrhenius equation, energy of activation, steady-state approximation.
7. Thermodynamics-I (6 Hours): Zeroth and first law, intensive/extensive variables, state/path functions, heat, work, internal energy, enthalpy, heat capacities, calculations for reversible/irreversible/free expansion, thermochemistry, bond energy, Kirchhoff’s equations, adiabatic flame temperature.

Practical (Credit: 1)

1. Separation, Purification, and Melting Point Determination (6 Hours): Separation of binary solid mixture using solvents (water, HCl, NaOH, NaHCO₃), purification by crystallization, melting point determination (e.g., benzoic acid/p-toluidine).
2. Determination of Boiling Point (6 Hours): Boiling points of organic liquids (ethanol, cyclohexane, ethyl methyl ketone, etc., <160°C).
3. Identification of Pure Organic Compound by Chemical Test(s) (3 Hours): Solids (oxalic acid, succinic acid, etc.), liquids (acetic acid, ethyl alcohol, etc.).

Reference Books:

• • Lee, J. D. Concise Inorganic Chemistry, ELBS, 1991.
  • Douglas, B.E. and McDaniel, D.H. Concepts & Models of Inorganic Chemistry, Oxford, 1970.
  • Atkins, P. Shriver & Atkins’ Inorganic Chemistry, 5th Ed., Oxford University Press, 2010.
  • Clayden, J., Greeves, N. & Warren, S. Organic Chemistry, Second edition, Oxford University Press, 2012.
  • Atkins, P. W. & Paula, J. de Atkins’ Physical Chemistry, Oxford University Press.
  • Bhattacharyya, R. C. A Manual of Practical Chemistry.
  • Vogel, A. I. Elementary Practical Organic Chemistry, Part 2: Qualitative Organic Analysis, CBS Publishers.

CHEM1021: General Chemistry-I

Credits: 3+1, Marks: 75 (Th: 40, Prac: 20, IA: 15)

Course Objective:

• Several fundamental aspects of the subject are discussed so that the principles can be useful for studying other branches of science.
• Practical experiments are designed for hands-on training in chemistry at the primary level.

Course Outcome:

Students will have an idea of chemical sciences, which may be applied for in-depth study of other science streams.

Theory (Credit: 3)

1. Atomic Structure (6 Hours): Bohr’s theory for hydrogen atom, atomic spectra, Sommerfeld’s model, quantum numbers, Pauli’s exclusion principle, Hund’s rule, Aufbau principle.
2. Periodic Properties (6 Hours): Classification of elements, characteristics of s-, p-, d-, f-block elements, positions of hydrogen and noble gases, atomic/ionic radii, ionization potential, electronegativity.
3. Acids and Bases (7 Hours): Bronsted-Lowry concept, conjugate acids/bases, Lewis concept, Lux-Flood concept, HSAB concept, acidity/basicity of organic compounds.
4. Aliphatic Hydrocarbons (10 Hours): Alkanes (preparation: hydrogenation, Wurtz, Kolbe’s synthesis; reactions: halogenation), alkenes (preparation: dehydration, dehydrohalogenation; reactions: addition, ozonolysis), alkynes (preparation: from CaC₂; reactions: metal acetylides, ozonolysis).
5. Ideal and Real Gases (5 Hours): Pressure, temperature, compressibility factor, van der Waals equation, critical state, viscosity of gases.
6. Thermodynamics-I (7 Hours): Zeroth/first law, heat, work, internal energy, enthalpy, thermochemistry, bond energy, Kirchhoff’s equation.
7. Chemical Kinetics-I (4 Hours): Rate law, order, molecularity, first-, second-, n-th order reactions, Arrhenius equation.

Practical (Credit: 1)

1. Determination of Boiling Points (8 Hours): Boiling points of organic liquids (ethanol, cyclohexane, etc.).
2. Identification of Pure Organic Compound (7 Hours): Solids (oxalic acid, succinic acid, etc.), liquids (acetone, aniline, etc.).

Reference Books:

• • Lee, J. D. Concise Inorganic Chemistry, ELBS, 1991.
  • Clayden, J., Greeves, N. & Warren, S. Organic Chemistry, Second edition, Oxford University Press, 2012.
  • Atkins, P. W. & Paula, J. de Atkins’ Physical Chemistry, Oxford University Press.
  • Vogel, A. I. Elementary Practical Organic Chemistry, Part 2: Qualitative Organic Analysis, CBS Publishers.

CHEM1031: Chemistry for Household Importance

Credits: 3, Marks: 50 (Th: 40, IA: 10)

Course Objective:

Several topics related to everyday life have been included to grow interest among students for the subject.

Course Outcome:

After studying the topics, these may help the students to get employment.

Theory (Credit: 3)

1. Food Chemistry (8 Hours): Food additives, flavors, adulterants, preservatives, artificial sweeteners.
2. Drugs and Pharmaceuticals (8 Hours): Structure and function, antipyretic and analgesic drugs (aspirin, paracetamol, ibuprofen).
3. Vitamins (2 Hours): Vitamin C and B₁₂.
4. Antibiotics (4 Hours): Penicillin, sulphaguanidine, chloramphenicol.
5. Glass and Ceramics (6 Hours): Manufacture of glasses, optical and colored glasses.
6. Surface Chemistry (2 Hours): Soaps and detergents.
7. Chemistry of Fuels (15 Hours): Conventional/non-conventional energy sources, classification, calorific values (kerosene, coal, petrol, LPG), octane number, biogas.

Reference Books:

• Thapar, Food Chemistry, Pacific Book International.
• Gayatri Baidya, Textbook of Food Chemistry, Book Rivers.
• Mandal, S.K., Pharmaceutical Chemistry and Production, Bentham Science Publishers, 2022.
• Sengupta, S., Application Oriented Chemistry, Books Syndicate Pvt. Ltd., 2000.

CHEM1051: Drugs and Pharmaceuticals

Credits: 3, Marks: 50 (Th: 40, IA: 10)

Course Objective:

• Design and development of several organic drugs.
• Detailed discussion for a clear idea about drugs, their synthesis, and physiological action.

Course Outcome:

The clear idea about drugs may not only grow general sense about their synthesis and mode of action but also help students have employment in the pharmaceutical industry.

Theory (Credit: 3)

Drug Discovery, Design, and Development (45 Hours): Synthesis of analgesics, antipyretics, anti-inflammatory agents (aspirin, paracetamol, ibuprofen), antibiotics (penicillin, chloramphenicol), antibacterial/antifungal agents (sulphonamides, sulphamethoxazole, sulphacetamide, trimethoprim), antiviral agents (acyclovir), CNS agents (phenobarbital, diazepam), cardiovascular (glyceryl trinitrate), antileprosy (dapsone), HIV-AIDS drugs (AZT-Zidovudine).

Reference Books:

• Patrick, G. L. Introduction to Medicinal Chemistry, Oxford University Press, UK, 2013.
• Singh, H. & Kapoor, V.K. Medicinal and Pharmaceutical Chemistry, Vallabh Prakashan, 2012.
• Foye, W.O., Lemke, T.L. & William, D.A., Principles of Medicinal Chemistry, 4th ed., B.I. Waverly Pvt. Ltd.
• Prescott & Dunn’s Industrial Microbiology, CBS Publisher, 2004.

CHEM2011: Basic Chemistry-II

Credits: 3+1, Marks: 75 (Th: 40, Prac: 20, IA: 15)

CHEM2021: General Chemistry-II

Credits: 3+1, Marks: 75 (Th: 40, Prac: 20, IA: 15)

CHEM2031: Chemistry of Dyes, Pigments, Cosmetics and Perfumes

Credits: 3, Marks: 50 (Th: 40, IA: 10)

CHEM2051: Basic Analytical Chemistry

Credits: 3, Marks: 50 (Th: 40, IA: 10)

CHEM3011: Inorganic Chemistry (Theory)

Credits: 5, Marks: 75 (Th: 40, IA: 15)

CHEM3012: Inorganic Chemistry (Practical)

Credits: 5, Marks: 75 (Th: 40, IA: 15)

CHEM3031: Chemistry of Soil and Fertilizer

Credits: 3, Marks: 50 (Th: 40, IA: 10)

CHEM3051: IT Skill in Chemistry

Credits: 3, Marks: 50 (Th: 40, IA: 10)

CHEM4011: Organic Chemistry (Theory)

Credits: 5, Marks: 75 (Th: 40, IA: 15)

CHEM4012: Physical Chemistry (Theory)

Credits: 5, Marks: 75 (Th: 40, IA: 15)

CHEM4013: Organic Chemistry (Practical)

Credits: 5, Marks: 75 (Th: 40, IA: 15)

CHEM4021: General Chemistry-III

Credits: 3+1, Marks: 75 (Th: 40, Prac: 20, IA: 15)